The 30-share BSE Sensex fell 34 points to 24770.28 and the 50-share NSE Nifty declined 17.25 points to 7521.50.
Lupin crashed 6 percent on Goa facility inspection by USFDA. HDFC and Sun Pharma declined over a percent while Infosys, SBI, TCS, L&T, Axis Bank and Maruti Suzuki gained 0.2-0.8 percent.
The Indian rupee has opened lower by 11 paise at 67.22 per dollar against 67.11 a dollar in previous session.
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